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Thesis

Single molecule studies of seven transmembrane domain proteins

Abstract:

This work aimed at studying biophysical properties of two membrane proteins, one of potential nanotechnological use, bacteriorhodopsin, and one potential drug target, the NTS1 neurotensin receptor, at the single molecule scale.

Bacteriorhodopsin (BR) is the only protein in the purple membrane (PM) of the halophilic organism Halobacterium salinarium. It is a light-driven proton pump converting light into a transmembrane proton gradient through isomerization of its retinal c...

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Institution:
University of Oxford
Department:
Medical Sciences Division - Biochemistry
Role:
Author

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Role:
Supervisor
Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:ff7ae71d-5481-4523-812b-2128fe32f5fc
Local pid:
ora:6415

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