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Impact of NICE guidance on tamoxifen prescribing in England 2011–2017: an interrupted time series analysis

Abstract:
Background Tamoxifen was recommended by NICE in 2013 for chemoprevention of breast cancer, but a recent survey suggested only a quarter of GPs are aware of this. We set out to measure the uptake of tamoxifen, and the alternative raloxifene, in national prescribing data sets. Methods Tamoxifen and raloxifene data were extracted from England’s monthly prescribing data sets, October 2010–October 2017. We used interrupted time series analysis to reveal national ... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41416-018-0065-2

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Primary Care Health Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
ORCID:
0000-0003-4932-6135
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Primary Care Health Sciences
Role:
Author
More from this funder
Name:
NIHR Biomedical Research Centre Oxford
Funding agency for:
Goldacre, B
Grant:
School of Primary Care Research
More from this funder
Name:
National Institute for Health Research
Funding agency for:
Goldacre, B
Grant:
School of Primary Care Research
More from this funder
Name:
Health Foundation
Funding agency for:
Goldacre, B
Grant:
School of Primary Care Research
Publisher:
Springer Nature
Journal:
British Journal of Cancer More from this journal
Volume:
118
Pages:
1268–1275
Publication date:
2018-04-23
Acceptance date:
2018-03-05
DOI:
EISSN:
1532-1827
ISSN:
0007-0920
Language:
English
Pubs id:
pubs:844821
UUID:
uuid:f688c155-5966-41c2-b187-b7293374ebc1
Local pid:
pubs:844821
Source identifiers:
844821
Deposit date:
2018-04-30

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