Thesis icon

Thesis

Right ventricular outflow limitation and capacity for exertion associated with age and iron status

Abstract:

This thesis is concerned with the role of iron in modulating right ventricular (RV) afterload during exercise in healthy people aged between 50 and 80 years. This is predicated on the requirement of the hypoxia-inducible factor (HIF) pathway for ferrous iron. A secondary objective is to examine the reactive oxygen species (ROS) hypothesis in human hypoxic pulmonary vasoconstriction (HPV) using exposure to hyperoxia.

Chapters 3 and 4 describe basal relationships that may affect the H...

Expand abstract

Actions


Access Document


Files:

Authors


More by this author
Department:
University College
Role:
Author

Contributors

Department:
University College
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP