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Thesis

Nanomedicine: development of a tri-imageable nanoparticle for diagnostics

Abstract:

Targeted, controlled, and noninvasive delivery of therapeutics is a major goal of pharmaceutical development. However, few techniques allow imaging and controlled drug release at the cellular level. Herein, a potential targeted drug delivery platform with three imaging reporters has been developed by coupling the magnetic properties of ultrasmall superparamagnetic iron oxide nanoparticles (USPIOs) with near infrared fluorescence of Cy5.5 and γ-emissions of 111In that is chelated...

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Department:
Oxford, MPLS, Engineering Science
Role:
Copyright Holder, Author

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Department:
Oxford, MPLS, Engineering Science
Role:
Supervisor
Department:
Oxford, MSD, Weatherall Institute of Molecular Medicine
Role:
Supervisor
Role:
Supervisor
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
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