Thesis
Modelling and simulation of phenotypic variability in cardiac tissue and application to stem cell-derived cardiomyocytes
- Abstract:
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Prediction of the safety of a novel pharmaceutical compound at the earliest possible stage of development is of great importance for drug discovery. Cardiac side-effects are a particular cause for concern, with several drugs such as Terfenadine and Cisapride having being withdrawn from the market due to adverse events. Investigation of the properties of novel compounds can be facilitated by the use of in silico models, which can provide a high-throughput and low-cost method of translating ...
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Funding
+ Engineering & Physical Sciences Research Council
More from this funder
Funding agency for:
Bowler, L
Grant:
EP/F500394/1
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
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uuid:a138d837-be95-487e-87e5-e1cf4769e9a4
- Deposit date:
- 2019-06-26
Related Items
Terms of use
- Copyright holder:
- Bowler, L
- Copyright date:
- 2018
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