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Thesis

Immunisation of children and adolescents against COVID-19: immunogenicity and reactogenicity of heterologous and fractional dose schedules

Abstract:

COVID-19 vaccination has been shown to protect children and adolescents against SARS-CoV-2 infection and disease, with efficacy increasing with additional doses. However, the increased risk of myocarditis associated with mRNA vaccination in adolescents, particularly following a seconddose, suggests a potential role for fractional or heterologous second doses. Data regarding heterologous and fractional dose COVID-19 vaccine schedules in adolescents, however, are lacking. Additionally, the decl...

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Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Supervisor
ORCID:
0000-0002-0855-2737
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Supervisor
ORCID:
0000-0003-1701-1390
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Supervisor
ORCID:
0000-0002-6063-8896
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Supervisor



DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford


Language:
English
Pubs id:
2407709
Local pid:
pubs:2407709
Deposit date:
2026-03-25
ARK identifier:

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