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Molecular and cellular features of anteromedial gonarthrosis

Abstract:

Anteromedial Gonarthrosis (AMG) is a distinct phenotype of knee osteoarthritis (OA), with a specific pattern of disease on the tibia. There is full thickness cartilage loss anteromedially, progressing to an area of damaged cartilage, and then to an area of macroscopically and histologically normal cartilage posteriorly. This reproducible pattern of disease can be considered to be a spatial model of OA progression and provides an alternative and less biologically varied set of specimens tha...

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Role:
Supervisor
Role:
Supervisor
Institution:
University of Oxford
Research group:
Price/Hulley
Oxford college:
Worcester College
Department:
Medical Sciences Division - NDORMS (Nuffield Department of Orthopaedics,Rheumatology and Musculoskeletal Sciences)
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:29c40452-7641-4884-8ab4-ec2ad7cb4152
Local pid:
ora:7635
Language:
English
Keywords:
Subjects:

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