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Thesis

Analysis methods for single molecule fluorescence spectroscopy

Abstract:

This thesis describes signal analysis methods for single-molecule fluorescence data. The primary factor motivating method development is the need to distinguish single-molecule FRET fluctuations due to conformational dynamics from fluctuations due to distance-independent FRET changes.

Single-molecule Förster resonance energy transfer (FRET) promises a distinct advantage compared to alternative biochemical methods in its potential to relate biomolecular structure to function. Standard...

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Institution:
University of Oxford
Division:
MPLS
Department:
Physics
Subgroup:
Condensed Matter Physics
Research group:
Kapanidis
Oxford college:
St Cross College
Role:
Author

Contributors

Division:
MPLS
Department:
Physics
Role:
Supervisor
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Grant:
Funding agency for:
Gryte, K
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:148969c6-78aa-49c2-8f0e-2d5e5018fd98
Local pid:
ora:7211
Language:
English
Keywords:
Subjects:

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