Background: Populations of East Africa including Sudan, exhibit some of the highest indices of genetic diversity in the continent and worldwide. The current study aims to address the possible impact of population structure and population stratification on the outcome of case-control association-analysis of malaria candidate-genes in different Sudanese populations, where the pronounced genetic heterogeneity becomes a source of concern for the potential effect on the studies outcome. Methods: A...Expand abstract
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- Eid et al.
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- Citation: Eid, N. A. et al. (2010). 'Candidate malaria susceptibility/protective SNPs in hospital and population-based studies: the effect of sub-structuring', Malaria Journal 9:119. [Available at http://www.malariajournal.com/content/9/1/119]. © 2010 Eid et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Candidate malaria susceptibility/protective SNPs in hospital and population-based studies: the effect of sub-structuring
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