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Thesis

Mathematical modelling of platelet production

Abstract:

Hospitals sometimes experience shortages of donor blood platelet supplies, motivating research into in vitro production of platelets. We use mathematical modelling to study platelet production.

First, we model the flow in a novel platelet bioreactor described by our collaborators in Shepherd et al. The bioreactor consists of an upper channel, a lower channel, and a cell-seeded porous collagen scaffold situated between the two. Flow is driven by gravity, and controlled by valves on ...

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Division:
MPLS
Department:
Mathematical Institute
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Role:
Supervisor
Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Role:
Supervisor
More from this funder
Name:
Engineering and Physical Sciences Research Council
Funder identifier:
http://dx.doi.org/10.13039/501100000266
Grant:
2100109
Programme:
Mathematical model for of thrombopoiesis
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
DOI:

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