Thesis
Sources of error in uncovering of the low level mitochondrial heteroplasmy landscape
- Abstract:
-
As organelles descendant from an ancient endosymbiont, mitochondria retain their own short circular genomes, with multiple copies of the mitochondrial DNA (mtDNA) distributed through the mitochondrial network within a cell. The multi-copy nature of the mitochondrial genome enables variant mtDNA copies to coexist within the same cell or organism. This well documented phenomenon, known as heteroplasmy, is a key feature of mitochondrial genetics that distinguishes mtDNA from its nuclear counterp...
Expand abstract
Actions
Access Document
- Files:
-
-
(Preview, Dissemination version, pdf, 73.7MB, Terms of use)
-
(Supplementary materials, zip, 237.5MB, Terms of use)
-
Authors
Contributors
+ Vaux, D
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Pathology Dunn School
- Oxford college:
- Lincoln College
- Role:
- Supervisor
+ Biotechnology and Biological Sciences Research Council
More from this funder
- Funder identifier:
- https://ror.org/00cwqg982
- Funding agency for:
- Sadurska, D
- Grant:
- BB/M011224/1
- Programme:
- Interdisciplinary Bioscience DTP
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
-
English
- Keywords:
- Subjects:
- Deposit date:
-
2026-02-17
- ARK identifier:
Terms of use
- Copyright holder:
- Daina Sadurska
- Copyright date:
- 2024
If you are the owner of this record, you can report an update to it here: Report update to this record