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Journal article : Letter

Malaria is a cause of iron deficiency in African children

Abstract:

Malaria and iron deficiency (ID) are common and interrelated public health problems in African children. Observational data suggest that interrupting malaria transmission reduces the prevalence of ID1. To test the hypothesis that malaria might cause ID, we used sickle cell trait (HbAS, rs334), a genetic variant that confers specific protection against malaria2, as an instrumental variable in Mendelian randomization analyses. HbAS was associated with a 30% reduction in ID among children living...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41591-021-01238-4

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Name:
Wellcome Trust
Grant:
110255/Z/15/Z
Publisher:
Springer Nature
Journal:
Nature Medicine More from this journal
Volume:
27
Issue:
4
Pages:
653–658
Publication date:
2021-02-22
Acceptance date:
2021-01-12
DOI:
EISSN:
1546-170X
ISSN:
1078-8956
Language:
English
Keywords:
Subtype:
Letter
Pubs id:
1140464
Local pid:
pubs:1140464
Deposit date:
2020-11-05

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