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Thesis

Biologic therapies and the need for hip and knee replacement amongst patients with rheumatoid arthritis: A population-based epidemiology study using electronic medical records and registry data

Alternative title:
Impact of biologics on need for joint replacement in RA
Abstract:

Registry reports indicate over 200,000 hip or knee replacements are performed annually in England, Wales and Northern Ireland, with approximately 1-2% carried out for inflammatory conditions such as rheumatoid arthritis (RA). The aim of this DPhil was to estimate the impact of biologic therapies on the need for major joint replacement amongst RA patients using observational health data.

An interrupted time-series analysis was used to estimate the impact of NICE approval of biologic...

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Supervisor
Department:
University of Bristol
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Supervisor
More from this funder
Name:
NIHR Clinician Scientist Award
Grant:
CS-2013-13-012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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