- Impact of biologics on need for joint replacement in RA
Registry reports indicate over 200,000 hip or knee replacements are performed annually in England, Wales and Northern Ireland, with approximately 1-2% carried out for inflammatory conditions such as rheumatoid arthritis (RA). The aim of this DPhil was to estimate the impact of biologic therapies on the need for major joint replacement amongst RA patients using observational health data.
An interrupted time-series analysis was used to estimate the impact of NICE approval of biologic...Expand abstract
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