The centriole in evolution: from motility to mitosis

Thesis

Centrioles and basal bodies with their characteristic 9+2 structure are found in all major eukaryotic lineages. The correlation between the occurrence of centrioles and the presence of cilia/flagella, but not centrosome-like structures, suggests that the ciliogenesis function of centrioles is ancestral. Here, it is demonstrated that the centriole domain of centrosomes emerged within the Metazoa from an ancestral state of possessing a centriole with basal body function but no funct...

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Authors: Smith, A

• Publication date: 2013
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: Oxford University, UK
• Language: English
• Keywords: axoneme; flagella; Centriole; Leishmania; basal body; evolution; amastigote; centrosome
• Subjects: Zoological sciences; Evolution (zoology)