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Thesis

Host and viral factors that determine the clinical outcome of hepatitis C virus genotype 3a infection

Abstract:

HCV infects 170 million persons worldwide and is a serious global health problem. Genotype-3a is the dominant genotype in newly diagnosed infections within the UK and has a high response rate to interferon therapy, with up to 70% patients achieving a sustained virological response (SVR). The reason(s) for this are unknown; therefore the aim was to assess host and viral factors that determine treatment outcome of subtype-3a infection.

Full-length subtype-3a viral sequence analysis ide...

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Institution:
University of Oxford
Oxford college:
Wolfson College
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of
Role:
Author

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Role:
Supervisor
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Funding agency for:
Isla Sheree Humphreys
Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
URN:
uuid:efe4f97b-5f82-4e8a-8ed5-18b71c5f00db
Local pid:
ora:6682

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