Thesis
Metabolism in mood disorder across the gut-liver-brain axis
- Abstract:
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Background and Aims: Depression and nonalcoholic fatty liver disease (NAFLD) are common disorders that share a bidirectional relationship and continue to increase in prevalence. Both maternal depression and obesity during pregnancy increase the risk of neuropsychiatric disease in the offspring. Alterations to systemic immunity and gut microbiota composition are thought to contribute to these relationships, though the precise mechanisms are not known. In rodents, probiotic sup... Expand abstract
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- Files:
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(Preview, Dissemination version, pdf, 12.8MB, Terms of use)
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Authors
Contributors
+ Anthony, D
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Pharmacology
- Sub department:
- Pharmacology
- Role:
- Supervisor
+ Burnet, P
- Role:
- Supervisor
+ Probert, F
- Institution:
- University of Oxford
- Division:
- MPLS
- Department:
- Chemistry
- Role:
- Supervisor
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
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English
- Subjects:
- Pubs id:
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2360175
- Local pid:
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pubs:2360175
- Deposit date:
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2022-11-23
- ARK identifier:
Terms of use
- Copyright holder:
- Radford-Smith, DE
- Copyright date:
- 2022
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