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The role of the aryl hydrocarbon receptor in Helicobacter pylori infection

Abstract:

The gastric pathogen Helicobacter pylori is a master of immune evasion and the main risk factor for developing non-cardia gastric cancer. The bacterium has evolved numerous strategies to evade the immune response launched by the infected host, enabling it to persist on the epithelium of the stomach for decades, despite chronic inflammation of the stomach mucosa. While many evasion mechanisms have been discovered, it is unknown as of yet, how the bacterium evades the strong NF-κB-driven inflam...

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Institution:
University of Oxford
Division:
MSD
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Oxford Ludwig Institute
Research group:
Boccellato
Role:
Supervisor
ORCID:
0000-0001-6013-7154
Institution:
University of Oxford
Division:
MSD
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Examiner
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
DOI:

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