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Thesis

Epigenetic regulation of postnatal subventricular zone development

Abstract:

The postnatal/adult subventricular zone (SVZ) harbours neural stem cells (NSC), which produce neurons that migrate to the olfactory bulbs. SVZ NSC share several biological features with glia, especially reactive astrocytes. However, it is not clear how SVZ NSC simultaneously maintain self-renewal stem cell properties and the potential for generating daughter cells that differentiate into neurons.

Multiple cyclin-dependent kinase inhibitors (CDKIs), including p16, p19 and p21 have be...

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Department:
University of Oxford

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Department:
University of Oxford
Role:
Examiner
Department:
University of Cambridge
Role:
Examiner
Department:
University of Oxford
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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