Thesis
Electrophysiological properties of striatal neurons in the dopamine-intact and Parkinsonian brain
- Abstract:
-
The striatum is the major input structure of the basal ganglia, and is composed of two major populations of spiny projection neurons (MSNs), which give rise to the socalled direct and indirect pathways, and several types of interneuron. Dopaminergic inputs to striatum are critical for its proper function. Indeed, loss of dopaminergic neurons in Parkinsonism leads to motor disturbances, grossly disturbs striatal activity, and is associated with the emergence of excessively-synchronized netw...
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Authors
Contributors
+ Magill, PJ
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Pharmacology
- Role:
- Supervisor
+ Bolam, JP
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Pharmacology
- Role:
- Supervisor
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- UUID:
-
uuid:e4e84e31-bc00-43b2-a930-dc7fa4143b1a
- Deposit date:
-
2015-10-01
Terms of use
- Copyright holder:
- Vinciati, F
- Copyright date:
- 2015
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