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NMR studies on holo-CcmE and in vivo mutagenesis studies on the interaction between CcmC and CcmE

Abstract:

At least five different systems are responsible for the maturation of c-type cytochromes. System I, present in the mitochondria of photosynthetic organisms and most Gram-negative bacteria, is the most complex cytochrome c biogenesis system discovered. In the model organism Escherichia coli, more than 10 gene products work together to attach heme to the highly conserved CXXCH motif of the apo-cytochrome polypeptide. This system consists of proteins that chaperon...

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Division:
MSD
Department:
Biochemistry
Role:
Author

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Supervisor
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Supervisor
Medical Research Council More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:e2371780-40b8-4e90-85d8-30448c98ef50
Deposit date:
2018-01-29

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