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Thesis

Complexity-generating cascade reactions

Abstract:

The development of complexity-generating reactions for the synthesis of molecules containing multiple quaternary centres has the potential to provide access to new 3D templates for the pharmaceutical and agrochemical industries as well as the efficient synthesis of biologically active natural products and fragments thereof. This thesis describes the development of radical cascade methodologies for the synthesis of complex spiro[4.4]nonanes, containing three adjacent quaternary centres, fro...

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Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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