Thesis
Nucleic acid nanostructures as tags for cryo-electron microscopy
- Abstract:
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Cryo-electron microscopy (cryo-EM) is an indispensable tool for structural biologists, allowing the reconstruction of biomolecules in their native, hydrated state to nanometre, or sub-nanometre, resolution. Unfortunately in situ cryo-EM characterisation is currently limited by our ability to interpret micrographs and tomograms, as a low signal-to-noise ratio means different structures are usually difficult to distinguish. To overcome this limitation, microscopists often use cryo-EM tags: e...
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- Files:
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(Preview, Dissemination version, pdf, 434.6MB, Terms of use)
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Authors
Contributors
+ Turberfield, A
- Division:
- MPLS
- Department:
- Physics
- Sub department:
- Condensed Matter Physics
- Role:
- Supervisor
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
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English
- UUID:
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uuid:dd011b46-68f6-438c-9720-63b84dc3cd5c
- Deposit date:
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2020-02-11
- ARK identifier:
Terms of use
- Copyright holder:
- Silvester, E
- Copyright date:
- 2019
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