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Thesis

Identification and characterisation of myofibroblast markers in human colon and colorectal cancer microenvironment

Abstract:

Myofibroblasts (MFs) are one of the most significant stromal cell types in epithelia such as in the gut. They play an important role in regulating the normal colorectal stem cell niche and facilitating tumour initiation, growth and progression through inter-cell signalling. Abundant presence of MFs is often associated with poor prognosis in cancers. The aim of this project is to identify new myofibroblast markers to distinguish them from others cells in the stroma, and also to establish p...

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Authors


Lin-Ting Hsia More by this author
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Role:
Supervisor, Author
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Funding agency for:
Project
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Funding agency for:
Project
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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