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Thesis

The role of hippocampal calcium-permeable AMPA receptors in network activity and behaviour

Abstract:

Parvalbumin-expressing (PV+) interneurons within the hippocampus play important roles in controlling spike timing and spike rates in circuits within the hippocampus, a brain region widely associated with various aspects of memory and spatial navigation. Due to minimal expression of the GluR2 AMPA receptor subunit, excitatory synapses onto PV+ interneurons are dominated by inwardly rectifying, Ca2+-permeable AMPA receptors (CP-AMPARs); in contrast, many other cell types, including principal...

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Division:
MSD
Department:
Doctoral Training Centre - MSD
Role:
Author

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Role:
Supervisor
Role:
Supervisor


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Funding agency for:
Cooper, M


DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford


UUID:
uuid:da2d0a7b-1a8c-4743-afc4-32d845f04496
Deposit date:
2019-02-24
ARK identifier:

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