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Single-molecule chemistry studied using the protein pore -α-hemolysin

Abstract:

Single-molecule detection has provided insights into how molecules behave. Without the averaging effect of ensemble measurements, the stochastic behaviour of single molecules can be observed and intermediate steps in multistep transformations can be clearly detected. The single-molecule reactants range from small molecules (e.g. propene) to proteins of several tens of kDa (e.g. myosin). One single-molecule detection technique is single-channel electrical recording. This approach is based o...

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Subgroup:
Chemical Biology
Oxford college:
Trinity College
Role:
Author

Contributors

Division:
MPLS
Department:
Chemistry
Role:
Supervisor
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:d9f32132-a6ae-4d49-9649-7bf9cd4b0dd2
Local pid:
ora:6599

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