Thesis
Computational modelling of post-stroke brain injuries
- Abstract:
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The healthy functioning of the human brain depends on continuous and sufficient blood flow and metabolism. Severe interruptions in blood and oxygen supply can lead to energy impairment, and result in irreversible brain damage. In ischaemic stroke, a large reduction in blood supply leads to the breakdown of the blood-brain barrier (BBB) and reperfusion injury after reperfusion therapy. The increased BBB permeability disrupts the homeostasis of solutes between blood and interstitial fluid an...
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- Files:
-
-
(Preview, Dissemination version, pdf, 14.9MB, Terms of use)
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Authors
Contributors
+ Payne, SJ
- Role:
- Supervisor
+ Grau, V
- Institution:
- University of Oxford
- Division:
- MPLS
- Department:
- Engineering Science
- Role:
- Supervisor
- ORCID:
- 0000-0001-8139-3480
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
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English
- Keywords:
- Subjects:
- Deposit date:
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2024-07-06
- ARK identifier:
Terms of use
- Copyright holder:
- Chen, X
- Copyright date:
- 2024
- Licence:
- CC Attribution (CC BY)
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