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Thesis

Measurement and characterisation of microvesicles and nanovesicles in pregnancy and pre-eclampsia

Abstract:

Excessive release of syncytiotrophoblast vesicles (STBM) from the placenta into the maternal circulation may cause the inflammatory response, endothelial dysfunction and activation of the coagulation system characteristic of pre-eclampsia (PE). Consequently, other cell types including platelets, leukocytes, red blood cells (RBC) and endothelium may be activated to release cellular vesicles which exacerbate the disease. This thesis aimed to develop methodology for enumerating and phenotypin...

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Institution:
University of Oxford
Division:
MSD
Department:
Women's and Reproductive Health
Oxford college:
Mansfield College
Role:
Author

Contributors

Division:
MSD
Department:
Women's and Reproductive Health
Role:
Supervisor
Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:cee47c16-f6f5-4264-b104-9e44987ade6f
Local pid:
ora:6813
Deposit date:
2013-04-22

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