Modelling and monitoring nonlinear acoustic phenomena in high-intensity focused ultrasound therapy

Thesis

High intensity focused ultrasound (HIFU) provides a wide range of noninvasive therapies ranging from drug delivery to the destruction of kidney stones. In particular, thermal ablation by HIFU presents an effective noninvasive method for the treatment of deep seated solid tumours. HIFU’s further uptake is limited by a need for improved treatment planning and monitoring. Two nonlinear acoustic phenomena that play key roles in HIFU treatment: finite amplitude effects that lead to the ge...

Expand abstract

Authors: Jackson, E

• DOI: 10.5287/ora-orowjg2mp
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: Acoustics; MRI Thermometry; Nonlinear acoustics; KZK Equation; Passive Acoustic Mapping
• Subjects: High-intensity focused ultrasound