- Abstract:
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Protein-protein interactions (PPIs) across the cell envelope of Gram-negative bacteria are critical for mediating signal transduction pathways that underpin cellular homeostasis. The Ton and Tol Pal systems are two conserved, ancestrally related protein networks that are also required for bacterial pathogenesis. Both Ton and Tol-Pal traverse the periplasm to effect different functions at the outer membrane (OM). Tol-Pal is composed of a homologous complex of three inner membrane protein...
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Some thesis volumes scanned as part of the digitisation scheme funded by Dr Leonard Polonsky are currently unavailable due to sensitive material or uncleared third-party copyright content. We are attempting to contact authors whose theses are affected.
- Department:
- University of Oxford
- Role:
- Supervisor
- Department:
- University of Oxford
- Role:
- Examiner
- Department:
- University of Cambridge
- Role:
- Examiner
- Funding agency for:
- Project
- Funding agency for:
- Peter Holmes
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Keywords:
- Subjects:
- Copyright date:
- 2016
Thesis
Structure and mode of action of the TolA-TolB complex from Pseudomonas aeruginosa
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Authors
Contributors
+ Colin Kleanthous
+ John Vakonakis
+ Jane Clarke
Funding
+ Biotechnology and Biological Sciences Research Council
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+ Natural Sciences and Engineering Research Council of Canada
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