Thesis
Characterising the genetic architecture of common elastic tissue disorders using UK Biobank
- Abstract:
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Background
Elastic fibres are key extracellular matrix (ECM) components that provide elasticity to tissues throughout the body, allowing them to recover after deformation. Derangement of elastic fibres lead to cutaneous and systemic disorders that show elastic tissue pathology. To distinguish between rarer disorders of elastic tissue, and common disease, I have coined the term ‘elastopathies.’ Common elastopathies such as hiatus hernia, diverticular disease, haemor...
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(Preview, Dissemination version, pdf, 38.6MB, Terms of use)
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Authors
Contributors
+ Furniss, S
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- NDORMS
- Role:
- Supervisor
- ORCID:
- 0000-0003-2780-7173
+ Wiberg, A
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- NDORMS
- Role:
- Supervisor
- ORCID:
- 0000-0003-4944-123X
+ Zondervan, K
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Women's & Reproductive Health
- Role:
- Supervisor
- ORCID:
- 0000-0002-0275-9905
+ Royal College of Surgeons of England
More from this funder
- Funder identifier:
- https://ror.org/02qrg5a24
+ NIHR Oxford Musculoskeletal Biomedical Research Centre
More from this funder
- Funder identifier:
- https://ror.org/00aps1a34
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
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English
- Keywords:
-
- Subjects:
- Pubs id:
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2268846
- Local pid:
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pubs:2268846
- Deposit date:
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2025-07-14
- ARK identifier:
Terms of use
- Copyright holder:
- Waheed-Ul-Rahman Ahmed
- Copyright date:
- 2024
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