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Thesis

An integrative framework for computational modelling of cardiac electromechanics in the mouse

Abstract:

This thesis describes the development of a framework for computational modelling of electromechanics in the mouse, with the purpose of being able to integrate cellular and tissue scale observations in the mouse and investigate physiological hypotheses. Specifically, the framework is applied to interpret electromechanical coupling mechanisms and the progression of heart failure in genetically modified mice.

Chapter 1 introduces the field of computational biology and provides context ...

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Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Research group:
Computational Biology
Oxford college:
Wolfson College
Role:
Author

Contributors

Division:
MPLS
Department:
Computer Science
Role:
Supervisor
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Name:
Medical Research Council
Funding agency for:
Land, S
Grant:
G0800980
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:cc71aa3b-70f8-42fc-83c9-4c0b2899f965
Local pid:
ora:7007
Deposit date:
2013-07-15

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