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Scaling-up of multi-capsule depth filtration systems by modelling flow and pressure distribution

Abstract:

Scaling-up of filtration systems in the pharmaceutical industry to provide the correct filtration capacity is a complex process. When several filters are used in parallel, the pressure and flow distribution within the system can be modelled using well-established constitutive laws to a high degree of accuracy, as shown in this paper. By combining the model with experimental fouling data, it is also possible to accurately predict the flow and pressure distribution during an entire filtration r...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1016/j.seppur.2016.07.028

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Department:
Oxford, MPLS, Mathematical Institute
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Department:
Oxford, MPLS, Mathematical Institute
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Department:
Oxford, MPLS, Mathematical Institute
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Funding agency for:
Krupp, AU
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Funding agency for:
Griffiths, I
Publisher:
Elsevier Publisher's website
Journal:
Separation and Purification Technology Journal website
Volume:
172
Pages:
350-56
Publication date:
2016-07-05
Acceptance date:
2016-07-17
DOI:
ISSN:
1383-5866
Pubs id:
pubs:648600
URN:
uri:cc3a3020-2728-48df-ad6e-07ce6c27de91
UUID:
uuid:cc3a3020-2728-48df-ad6e-07ce6c27de91
Local pid:
pubs:648600

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