Thesis icon

Thesis

Structure of the PfEMP1:EPCR complex and inhibition of the interaction

Abstract:

The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family is central for Plasmodium falciparum infection. This family mediates interactions between the infected erythrocyte and the host endothelial surface, making it an obvious vaccine target. However this family is very diverse, with sixty different variants in the genome of each parasite. Despite the diversity within the PfEMP1 family, only around ten ligands have been identified. T...

Expand abstract

Actions


Access Document


Files:

Authors


More by this author
Department:
University of Oxford
Role:
Author

Contributors

Role:
Supervisor
Medical Research Council More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:cbbea8da-eea2-4628-827b-4ff7dda635c4
Deposit date:
2016-05-03

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP