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Thesis

Genetic susceptibility to common mycobacterial diseases

Abstract:

Common mycobacterial diseases, including tuberculosis and leprosy, contribute to major mortality and morbidity worldwide. Despite evidence of an important role of host genetic factors in susceptibility to these infections, few compelling genetic associations have been identified with previous candidate gene and linkage approaches.

This thesis investigates the genetic factors of human immunity to these mycobacterial diseases using a high-throughput approach of association testing. To ...

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Institution:
University of Oxford
Research group:
Genetics of Inflammation and Immunity
Oxford college:
Green College
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of - Wellcome Trust Centre for Human Genetics
Role:
Author

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Publication date:
2010
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:cb4dd818-4693-4168-ad8a-cdeb59e2d5f3
Local pid:
ora:6392

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