Genomic data analyses for population history and population health

Thesis

Many of the patterns of genetic variation we observe today have arisen via the complex dynamics of interactions and isolation of historic human populations. In this thesis, we focus on two important features of the genetics of populations that can be used to learn about human history: population structure and admixture. The Iberian peninsula has a complex demographic history, as well as rich linguistic and cultural diversity. However, previous studies using small genomic regions (such as Y...

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Authors: Bycroft, C

• DOI: 10.5287/ora-orrxp42jo
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: Big data; Genotyping arrays; Demographic history; Iberian Peninsula; Population genetics; Quality control; GWAS; Human genetics