Thesis
Development of mycobacterial growth inhibition assays for the early evaluation and gating of novel TB vaccine candidates
- Abstract:
-
Tuberculosis poses a serious global health threat, with an estimated 9 million new cases and 1.5 million deaths annually. The current vaccine, BCG, is inadequate but development of an effective alternative is severely hampered by the lack of an immune correlate of protection. Candidate vaccines are currently tested using preclinical animal models such as mice and non-human primates. Large numbers of animals are required and subjected to procedures classified as 'Moderate' in severity. Expe...
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Authors
Contributors
+ McShane, H
Department:
University of Oxford
Role:
Supervisor
+ Fletcher, H
Department:
London School of Hygiene and Tropical Medicine
Role:
Supervisor
Funding
Universities Federation for Animal Welfare
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Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:c85b98a6-e10a-4197-a88f-0da31b8169c6
- Deposit date:
- 2016-01-07
Terms of use
- Copyright holder:
- Tanner, R
- Copyright date:
- 2015
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