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Thesis

Fine-mapping complex traits in heterogeneous stock rats

Abstract:

The fundamental theme my thesis explores is the relationship between genetic variation and phenotypic variation. It addresses three main questions. What is the genetic architecture of traits in the HS? How can sequence information help identifying the sequence variants and genes responsible for phenotypic variation? Are the genetic factors contributing to phenotypic variation in the rat homologous to those contributing to variation in the same phenotype in the mouse?

To address these...

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Institution:
University of Oxford
Research group:
Mott, Flint groups
Oxford college:
Wadham College
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of - Wellcome Trust Centre for Human Genetics

Contributors

Role:
Supervisor
Role:
Supervisor
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Funding agency for:
Amelie Baud
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:c762c1af-c899-478f-93e1-305775d5a6f4
Local pid:
ora:8667

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