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Thesis

Factors influencing damage to cerebral white matter in the elderly

Abstract:

BACKGROUND: White matter hyperintensities (WMH) appearing on magnetic resonance images (MRI) occur in the non-demented and demented elderly. Age is an established risk factor associated with WMH. Other possible risk factors include sex, smoking, hypertension, biochemical markers and genotypes associated with B vitamin status, and APOE ε4 status. WMH have been associated with an increased risk of depression and cognitive dysfunction.

OBJECTIVES: To investigate factors associated with ...

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Institution:
University of Oxford
Research group:
Oxford Project to Investigate Memory and Aging (OPTIMA)
Oxford college:
Lady Margaret Hall
Department:
Medical Sciences Division - Physiology,Anatomy and Genetics,Department of

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Role:
Supervisor
Publication date:
2009
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
Oxford University, UK
URN:
uuid:c620b596-ad20-4881-9016-0f5a015e8ffb
Local pid:
ora:6357

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