Synthesis of the CDE & EFG ring systems of pectenotoxin-4

Thesis

This thesis explores new synthetic routes for the formation of CDE & EFG fragments of pectenotoxin-4.

Chapter 1: Introduction and Previous Work

This chapter reviews the discovery and biological activities of members of the pectenotoxin family. Two previous total syntheses are discussed, and previous work regarding the synthesis of ABC, E and FG fragments within the group is introduced.

Chapter 2: Synthesis of the E Ring Fragment of Pectenotoxin-4

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Authors: Liu, Y

• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: pectenotoxin; total synthesis; organic chemistry; synthetic organic chemistry
• Subjects: Chemistry, Organic