Software architecture for capturing clinical information in hadron therapy and the design of an ion beam for radiobiology

Thesis

Hadron Therapy (HT) exploits properties of ion radiation to gain therapeutic advantages over existing photon-based forms of external radiation therapy. However, its relative superiority and cost-effectiveness have not been proven for all clinical situations. Establishing a robust evidence base for the development of best treatment practices is one of the major challenges for the field. This thesis investigates two research infrastructures for building this essential evidence.

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Authors: Abler, D

• Publication date: 2013
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: slow extraction; model-driven engineering; health informatics; evidence based medicine; data capture; case report form; ion beam; beam transport; radiobiology; synchrotron; charged particle therapy; software architectures; domain-specific model; markov model; metamodel; system description languages
• Subjects: Physics and CS; Particle physics; Applications and algorithms; Software engineering