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Thesis

Potential effects of assisted reproductive technology upon the abundance and localisation of two vital sperm proteins

Abstract:

Assisted reproductive technology (ART) uses advanced techniques such as in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI) to combat human infertility. However, the success rate of ART is poor and can, at least in part, be attributed to detrimental (iatrogenic) damage incurred by gametes and embryos during laboratory treatment or manipulation, thus compromising their functional role and reducing the chances of fertilisation. The sperm plays two fundamental roles upon...

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Institution:
University of Oxford
Oxford college:
Jesus College
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of Obstetrics and Gynaecology

Contributors

Role:
Supervisor
Publication date:
2015
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:be57f123-c6dc-4cc8-ae53-1f32716cc1e5
Local pid:
ora:11309

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