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Thesis

T cells in HBV associated hepatocellular carcinoma and other cancers

Abstract:

Individuals with HBV associated hepatocellular carcinoma or other cancers are characterized by dysfunctional anti-virus and anti-tumor T-cell responses. Since noteworthy benefits of inhibitory pathway blockades, such as PD-1 inhibitor or CTLA-4 inhibitor have been achieved in multiple advanced cancers, the next critical question is which mono- or combinatorial blockade regimens may reinvigorate anti-virus and anti-tumor T-cell immunity in multiple cancers. This thesis aims to comprehensive...

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Division:
MSD
Department:
Doctoral Training Centre - MSD
Role:
Author

Contributors

Role:
Supervisor
Role:
Supervisor


DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford


UUID:
uuid:bb17db80-554e-453c-8daa-c550fea30cc2
Deposit date:
2018-07-12
ARK identifier:

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