Journal article
Structural imaging of the cervical spinal cord with suppressed CSF signal using DANTE pulse trains.
- Abstract:
- PURPOSE: We propose DANTE (Delays Alternating with Nutation for Tailored Excitation) moving fluid attenuation preparation pulse trains, in conjunction with T1 , T2 , and proton-density-weighted fast spin-echo (T1w-TSE, T2w-TSE and PDw-TSE) imaging readout, and three-dimensional fast low flip angle shots (3D-FLASH) T1 -weighted imaging readout to achieve CSF-suppressed high-spatial resolution multicontrast cervical spinal cord images. METHODS: DANTE pulse trains, consisting of a rapid series of low flip angle radiofrequency pulses interspersed with gradients, were used to substantially attenuate the longitudinal magnetization of flowing spins relative to static tissue/fluid, whose longitudinal magnetization is mostly preserved. We hypothesized that the contrast between spinal cord and cerebrospinal fluid (CSF) could be maximized due to moving CSF signal suppression. RESULTS: We demonstrate that metrics of contrast-to-noise ratio between spinal cord, nerve root, and CSF regions (CNRcord-CSF and CNRnerve-CSF ) are improved by at least a factor of 2 when compared with images acquired with non-prepared approaches and with 2D multiple-echo data image combination (MEDIC) imaging. In addition, we find that sagittal image quality can be significantly improved due to flow suppression effects from the DANTE preparation pluses. CONCLUSION: DANTE prepared imaging techniques for moving CSF signal attenuation are promising tools for cervical spinal cord imaging. Magn Reson Med 74:971-977, 2015. © 2014 Wiley Periodicals, Inc.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Accepted manuscript, vnd.openxmlformats-officedocument, 509.2KB, Terms of use)
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- Publisher copy:
- 10.1002/mrm.25474
Authors
- Publisher:
- Wiley
- Journal:
- Magnetic resonance in medicine More from this journal
- Volume:
- 74
- Issue:
- 4
- Pages:
- 971-977
- Publication date:
- 2015-10-01
- DOI:
- EISSN:
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1522-2594
- ISSN:
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0740-3194
- Language:
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English
- Keywords:
- Pubs id:
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pubs:485461
- UUID:
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uuid:ba1fd853-7ce6-4150-8e02-a67461d90790
- Local pid:
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pubs:485461
- Source identifiers:
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485461
- Deposit date:
-
2014-10-04
Terms of use
- Copyright holder:
- Wiley Periodicals, Inc
- Copyright date:
- 2015
- Notes:
- Copyright © 2014 Wiley Periodicals, Inc. This is the peer reviewed version of the following article: Li, L., Kong, Y., Zaitsu, Y., Matthews, L., Palace, J. and Jezzard, P. (2015), Structural imaging of the cervical spinal cord with suppressed CSF signal using DANTE pulse trains. Magn Reson Med, 74: 971–977. doi: 10.1002/mrm.25474, which has been published in final form at 10.1002/mrm.25474. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
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