Quantitative measurements of cerebral hemodynamics using magnetic resonance imaging

Thesis

Cerebral ischemia is a vascular disorder that is characterized by the reduction of blood supply to the brain, resulting in impaired metabolism and finally death of brain cells. Cerebral ischemia is a major clinical problem associated with global morbidity and mortality rates of about 30%. Clinical management of cerebral ischemia relies heavily on perfusion analysis using dynamic susceptibility contrast MRI (DSC-MRI). DSC-MRI analysis is performed using mathematical models that simulate the...

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Authors: Mehndiratta, A

• Publication date: 2014
• DOI: 10.5287/ora-2rgmejdvr
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: dynamic susceptibility contrast MRI; stroke; perfusion; MRI; cerebral ischemia; control point interpolation
• Subjects: Biomedical engineering; Stroke; Probability; Numerical analysis; Medical Engineering; Radiology; Mathematical modeling (engineering); Medical sciences