Palladium-catalysed enolate arylation in the synthesis of aromatic heterocycles and substituted heterocycles

Thesis

Chapter 1. Introduction

A literature background on the early development of the Pd-catalysed cross-coupling reactions and the later discovery of the enolate arylation reaction is presented. In the second part, the literature on pyruvate chemistry is explored, focusing on enantioselective transformations and the synthesis of α-arylated pyruvate derivatives. The final part presents reported protocols on the synthesis of β-carboline, isoquinoline and indole esters, from the ...

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Authors: Esteves, C

• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford