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A comprehensive genomics solution for HIV surveillance and clinical monitoring in low income settings

Abstract:

Viral genetic sequencing can be used to monitor the spread of HIV drug resistance, identify appropriate antiretroviral regimes, and characterize transmission dynamics. Despite decreasing costs, next-generation sequencing (NGS) is still prohibitively costly for routine use in generalised HIV epidemics in low- and middle-income countries. Here, we present veSEQ-HIV, a high-throughput, cost-effective NGS sequencing method and computational pipeline tailored specifically to HIV, which can be perf...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1128/jcm.00382-20

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Division:
MSD
Department:
NDM
Sub department:
Big Data Institute
Role:
Author
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Publisher:
American Society for Microbiology Publisher's website
Journal:
Journal of Clinical Microbiology Journal website
Volume:
58
Issue:
10
Article number:
e00382-20
Place of publication:
United States
Publication date:
2020-07-15
Acceptance date:
2020-07-10
DOI:
EISSN:
1098-660X
ISSN:
0095-1137
Pmid:
32669382
Language:
English
Keywords:
Pubs id:
1120206
Local pid:
pubs:1120206
Deposit date:
2020-08-26

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