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Thesis

Functional analysis of the African swine fever virus MGF360 and MGF505 proteins, and its application to vaccine development

Abstract:

African swine fever virus (ASFV) is a deadly haemorrhagic pathogen of swine. In recent years, ASFV has spread beyond Africa and continues to ravage European and Asian pig herds, posing a severe socio-economic threat. No vaccines are currently available leaving preventive and extermination measures as the only course of action. The virus’ dsDNA genome is up to 190kb in length, and contains 5 clusters of paralogous genes known as Multigene family (MGF) genes close to both termini. Genes of MGF3...

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Division:
MSD
Role:
Author

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Role:
Contributor
Role:
Contributor
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Supervisor
ORCID:
0000-0002-6823-9750
Role:
Supervisor
Role:
Supervisor
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Name:
Biotechnology and Biological Sciences Research Council
Funder identifier:
http://dx.doi.org/10.13039/501100000268
Funding agency for:
Connell, S
Grant:
1801371
Programme:
Studentship
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Name:
Zoetis Inc.
Funding agency for:
Connell, S
Grant:
N/A
Programme:
iCASE
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
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Deposit date:
2023-02-10

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