Thesis
Characterisation of HBV and SARS-CoV-2 spike specific T cells and their association with viral control
- Abstract:
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T cell responses are crucial in viral clearance, but little is known of the role of cytotoxic CD4+ T cells in the control of viral infection.
Chronic hepatitis B virus (HBV) infection is a global public health problem. In the first part of my study, HBx-specific T cell responses were investigated in patients with chronic HBV infection and their functional profiles were evaluated in vitro. Stronger HBx-specific T cell responses were associated with HBeAg clearance and lower HBsAg le...
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- Files:
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(Preview, Dissemination version, pdf, 22.1MB, Terms of use)
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Authors
+ China Scholarship Council
More from this funder
- Funder identifier:
- https://ror.org/04atp4p48
- Funding agency for:
- Liu, G
- Grant:
- 201908060242
+ CAMS-University of Oxford Institute NDM
More from this funder
- Funding agency for:
- Liu, G
- Grant:
- SFF1819_MSD_1046702
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
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English
- Keywords:
- Subjects:
- Pubs id:
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1987771
- Local pid:
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pubs:1987771
- Deposit date:
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2024-03-26
- ARK identifier:
Terms of use
- Copyright holder:
- Guihai Liu
- Copyright date:
- 2023
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