Effect of β2-adrenergic receptor agonists on neurotransmission and neuromuscular junction structure in congenital myasthenic syndromes
Background: β2-adrenergic agonists have been reported to be beneficial in patients with congenital myasthenic syndromes, in particular in those subtypes where postsynaptic structure is impaired. Although the β2-adrenergic receptor is well known for its muscle actions, its working mechanism at the neuromuscular junction is not understood.
Aims: It was hypothesized that β2-adrenergic agonists improve neurotransmission by ameliorating postsynaptic structure in ...Expand abstract
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