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Thesis

Biophysical studies of membrane protein structure and function

Abstract:

Membrane proteins play a key role in numerous physiological processes such as transport, energy transduction in respiratory and photosynthetic systems, and signal transduction, and are of great pharmaceutical interest, comprising more than 60% of known drug targets. However, crystallisation of membrane proteins, and G protein-coupled receptors (GPCRs) in particular, still relies heavily on the use of protein engineering strategies, which have been shown to hamper protein activit...

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Institution:
University of Oxford
Research group:
Anthony Watts
Oxford college:
St Hugh's College
Department:
Medical Sciences Division - Biochemistry
Role:
Author

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Role:
Supervisor
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Funding agency for:
Patricia Dijkman
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:ad0fde85-c4b6-48a1-b51b-d304aca45402
Local pid:
ora:11745

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